prozone

prozone
Prozone phenomena occur in immunological reactions when the concentrations of antibody or other active immune agent are so high that the optimum concentration for maximal reaction with antigen is exceeded. Immunological phenomena in the prozone region may show partial or total inhibition.

Dictionary of molecular biology. 2004.

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Look at other dictionaries:

  • Prozone — In an agglutination or precipitation reaction, prozone or prezone is the zone of relatively high antibody concentrations within which no reaction occurs. In an agglutination test, a person s serum (which contains antibodies) is added to a test… …   Wikipedia

  • prozone — In the case of agglutination and of precipitation, the phenomenon in which visible reaction does not occur in mixtures of specific antigen and antibody because of antibody excess. SYN: prezone. * * * pro·zone …   Medical dictionary

  • prozone phenomenon — n the reduction in characteristic effect exhibited in the prozone of antibody antigen mixtures called also prozone effect …   Medical dictionary

  • prozone reaction — see prozone …   Medical dictionary

  • prozone — noun The range of antibody concentrations within which reaction is inhibited …   Wiktionary

  • prozone — pro·zone …   English syllables

  • prozone — ˈprōˌzōn noun Etymology: pro (I) + zone : the portion of the range of concentration of antibody antigen mixtures in which one of them although present in excess does not produce its characteristic effect (as agglutination or precipitation) …   Useful english dictionary

  • zone of antibody excess — prozone …   Medical dictionary

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